escubed offers physio-chemical characterisation of API’s and to the Pharmaceutical and Biotech industries to support preformulation studies and batch release. escubed has a host of analytical equipment and methods available along side experts scientists to provide a trustworthy and efficient service to suit our customer’s needs.

We aim to provide a cost-effective, flexible service including the following;

  • • Raw Materials Characterisation
  • • Stability Testing
  • • Polymorph Screening
  • • Crystallisation Screening

As experts in powders, particles and colloids, at escubed we pride ourselves on providing our customers with reliable and consistent data. Our techniques available include;

  • • Particle size
  • • Flowability
  • • BET Specific Surface Area

  • • Density
  • • Particle Shape – SEM / TEM
  • • X-Ray Powder Diffraction
  • • Wettability – Contact Angle

  • • Thermal – DSC / TGA / HSM
  • • DVS
  • • Rheological Assessment
• HPLC / ICP / MS / UV-Vis
  • • pH

What do our Pharmaceutical clients say?

Kyle Kleinbeck, Ph.D. Senior Scientist, International Partnership for Microbicides;

“I have enjoyed working with you all very much, and would be happy to be a reference. You assembled a fantastic team of internal and external experts in pre-formulation, and communication with that team has always been very timely and proactive. I receive status updates and data often before I even expect them. Your approach to communication has made it very easy for us to stay out in front of any potential issues that could have arisen in our project. The result was on-time completion and robust data that we can easily simply pass-through to the FDA or EMA.”

Environmental and Water

escubed offers a range of services to the environmental sector with a particular emphasis on the rheological assessment of sludges and slurries from water processing plants and the filters from Stack Emissions Testing for PM1, PM2.5 and PM10.

escubed’s expert scientists have vast experience with the measurement of sludges from the water treatment processes. We have experience measuring sewage and effluent from Anaerobic digestion processes. We are able to measure the particle size distribution (PSD) using laser diffraction to help understand the success of any filtration processes and rheological assessment of the sludges in order to provide valuable information on yield stresses and viscosity for pumping.

We also provide a bespoke service to the stack emissions sector whereby we are able to measure the particle size distribution of filters taken from stacks for the analysis of PM1, PM2.5 and PM10. This valuable data may be used to contribute to the MCERTS data in order to provide a full particle size distribution of the sample for a full understanding of the particle emissions.

Inks, Pigments and Paints

escubed has vast experience in both the development, formulation and production of inks and paints as well as offering full characterisation of these systems. escubed has recently completed a 2 year Innovate UK grant which involved both the development and production of catalyst inks for use in Fuel cells. We have also just commenced a second 3 year Innovate UK grant focused on the development of novel methods for the production of designer emulsions, including a functional paint for a large multinational paint manufacturer.

For the characterisation of these systems, we are able to measure the particle size distribution (PSD) of the pigments or toners with a range of particle size measuring systems available to us. For pigments with a particle size distribution in the micron range, we are able to use our Malvern Instrument’s Mastersizer 3000 or 2000 laser diffraction equipment or Beckman Coulter Multisizer IV if concentration of particulates as well as distribution is important. For inks with pigments or toner particles with a smaller PSD in the nanometer range we are able to utilise our Malvern Instrument’s Zetasizer or the CPS Disc Centrifuge.

We also have great experience in understanding the rheological behaviour of such systems, which is a particularly important aspect to have full control over in all types of inks and paints whether they are sprayed, screen printed or just applied at home with a paint brush with use of our Malvern Instrument’s Kinexus Ultra +.

For catalyst based inks for use in electrochemical cells or fuel cells it is also important to understand the BET surface area of the catalysts which escubed is able to measure using our state of the art equipment from Micromeritics.

For understanding the stability of the dispersed pigments or toner particles we can provide zeta potential measurements or provide data through accelerated stability in respect to sedimentation with the use of the LUMisizer.

XME Application Note

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